| | | | February 2023 Clinical Update: ASCO Guidelines for Germline Testing in Ovarian Cancer
| | The American Society of Clinical Oncology (ASCO) Guidelines for Ovarian Cancer focus on the screening, diagnosis, staging, treatment, and management considering individual risk assessment.
These updated guidelines include criteria for further genetic risk evaluation using a hereditary cancer panel for hereditary cancer syndromes: · All women diagnosed with ovarian cancer should be offered germline testing for BRCA1, BRCA2, and other ovarian cancer susceptibility genes, irrespective of their clinical features or family cancer history.
Germline testing should be ordered in appropriate individuals where it will impact the treatment, clinical trial options and risk management. The recommended panels should contain BRCA1, BRCA2, RAD51C, RAD51D, BRIP1, MLH1, MSH2, MSH6, PMS2, PALB2, and TP53.
Genetics Institute of America’s GIAnomics™ Oncology Germline Panel includes all the recommended predisposition genes for Ovarian Cancer. GIA is committed to exceeding the standards put forth by prestigious organizations, like ASCO, and ensuring that the panels we offer support your medical needs and your patient’s health and safety. | | | | Have you Seen This?:
PGx in Psychiatry and Primary Care In the year 2020, over 40% of the United States population reported one or more adverse mental health conditions, including Major Depressive Disorder (MDD).1 “64% of the United States depressed population reported severe impairment and were commonly treated with medication combined with care by a health professional.” Read more >>
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It's All in the Genes:
TP53 and Li-Fraumeni Spectrum Li-Fraumeni Syndrome (LFS) is caused by TP53 germline variants, which causes a person to be predisposed to a variety of cancers over their lifetime. This syndrome has yet to be fully understood, as there are a variety of phenotypes associated with these variants. The most important phenotypic differences include age at diagnosis and cancer type. Read more >>
| | | | Changing Corporate Culture: CityHouse 5K and Providing Care for Single Mothers Since being established in 2014, CityHouse of Delray Beach, Florida provides long-term, transformational assistance to mothers and their children. They help single mothers in need have better opportunities to develop healthy lifestyles, which enables them to provide sustainable, loving and proper care for their children. Read more >> | | | | | | | | Enroll your Practice in GH-101! | | Genetics Institute of America is actively recruiting practices to join our study, GH-101! The objective of this study is to take an integrative approach to the fields of pharmacogenomics, cancer genomics, mRNA microarrays and nutrigenomics by identifying DNA and RNA variants in persons with chronic disease. We are looking for Physicians and Physician Groups that currently treat patients with a chronic disease including: cancer, cardiac conditions, diabetes, kidney disease, PTSD. Getting your practice involved is easy and not only gets patients the individualized health information they need but allows your practice to be on the cutting edge of genetic research. | | | | | | Thank you for the trust and confidence you have placed in our team here at the Genetics Institute of America. This monthly newsletter is our primary method of communicating to you important information about our testing and assays, general information about the Genetics Institute, as well as information impacting patient care and safety. If you would like to have another person in your practice receive these updates, please forward this to them so that they can subscribe.
 Ana Perez-Miranda, PhD, MDxT (AAB), MB (ASCP) Laboratory Manager and Molecular Diagnostics Supervisor Genetics Institute of America | | | | | | | | | | GIA Lab News is an educational service of Genetics Institute of America.
Genetics Institute of America is a national laboratory dedicated to heightening the awareness of early intervention and genetic screening to promote the longevity and quality of life outcomes. Our determination and research allow us to provide next generation DNA sequencing to deliver customized testing for identified genetic related cancers and other diseases. | | | | | | 4733 W. Atlantic Ave, Suite C16 Delray Beach, FL 33445 Phone: (833) 4GENLAB or (833) 443-6522 HIPAA Fax: (561) 354-5369
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